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The liver is a storehouse for many enzymes and injury or disease
affecting the liver causes release of these enzymes into the bloodstream. Enzyme
tests that may indicate liver damage include the aspartate aminotransferase
AST and alanine aminotransferase ALT.
Other frequently tested liver enzymes that indicate biliary tract obstruction,
whether in the liver or in bile channels outside the liver, are alkaline
phosphatase ALP and gamma-glutamyltranspeptidase
GGT. These enzymes are also produced in other organs;
therefore, enzyme measurements are not specific for liver disease alone. In
addition to LFTs obtained on routine chemistry tests, the physician may order
more specific tests such as viral serologic tests or autoimmune tests, that can
determine the specific etiology of a liver disease. This web page uses frames, but your browser doesn't support them.