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L-lactate dehydrogenase (LD)

LDH-1: heart and RBCs
LDH-2: WBCs. It is also found in heart and red blood cells, but less than LDH-1.
LDH-3: lung tissue.
LDH-4: WBCs, kidney, pancreas cells, and lymph nodes.
LDH-5: found in the liver and skeletal muscles.

Source: https://medlineplus.gov/lab-tests/lactate-dehydrogenase-ldh-isoenzymes-test/

Lactate dehydrogenase is an important group of isoenzymes of the anaerobic metabolic pathway. A form of L-lactate dehydrogenase is present in the liver (LDH-5) and almost all body tissues.

Conditions that can cause increased LDH in the blood may include:

Anemia
Kidney disease
Liver disease
Muscle injury
Heart attack
Pancreatitis
Infections, including meningitis, encephalitis, and infectious mononucleosis (mono)
Certain types of cancer, including lymphoma and leukemia. A higher than normal LDH level may also mean treatment for cancer is not working (Medline 2020).

LDH is also a non-specific marker of tissue turnover, which is a normal metabolic process. Elevated levels may indicate liver damage but can be elevated in many other disorders.

U.S. National Library of Medicine. (2020). Lactate dehydrogenase (LDH) isoenzymes test: Medlineplus medical test. MedlinePlus. Retrieved October 11, 2021, from https://medlineplus.gov/lab-tests/lactate-dehydrogenase-ldh-isoenzymes-test/.